Many fans viewed any “fix” of the Spider‑Man books as unnecessary, arguing that the only thing the book requires is a good writer, who can make any status quo compelling. In this case, if a decade of Peter and Mary Jane being married became tiresome, that was the fault of the writers for not making it interesting.
One assumption made by a few proponents of the "good writers argument” is that the writers who dislike the marriage do so because they don’t understand how to write compelling women, due to a lack of the necessary skill or experience. That's a direct quote from an old CBR post. This can only be interpreted as a personal or professional insult against the writer, implying that every professional who prefers Peter Parker to be single is either untalented or socially retarded, thus denigrating the excellent writers who were opposed to the marriage including Kurt Busiek, Roger Stern, Ed Brubaker and even Quesada. His "The Mask in the Iron Man" arc was pretty damn good.
There are other insulting claims against proponents of breaking up the marriage. The oddest is the suggestion is that the writers, readers and editors who want Peter Parker to be single wish to live vicariously through him. If that were the case, I'd imagine we’d want him to remain married to the gorgeous supermodel actress redhead. He also wouldn’t ever get his ass kicked. "Unscheduled Stop" and the various Gauntlet stories were not written by anyone who wishes to experience what Spidey goes through.
Almost as silly is the argument that writers supported the retcon because they’re lazy, given the work required to pull it off, and the initial uncertainty of whether the readers will accept it. The difficulties continue for Dan Slott and Zeb Wells. It was challenging to come up with a reason for a character not accustomed with magic to encounter an individual with the ability and desire to change reality so that the protagonist is he’s no longer married to the love of his life. But it's going to be much more challenging for the writers to develop new romantic interests who will inevitably be compared to Mary Jane. Lazy writers would go for the cheap applause by reuniting the couple, keep the two married, exhaust the good “married Spider-Man” stories as quickly as possible and probably start giving the supporting cast the interesting private lives.
Good writers would tell good stories with the marriage, and have done so in the past. Look at Millar’s run on Marvel Knights Spider-Man, Matt Fraction’s Sensational Spider-Man annual or JMS’s Amazing Spider-Man, in addition to older material by Dematteis and Micheline. Due to the increased availability of hundreds of good Spider‑Man stories for the average reader, just "good" isn't going to cut it for new material, when readers are paying three bucks for something that will take them less than ten minutes to read. The relevant questions are whether good writers would be able to tell better stories if Peter Parker were not married to Mary Jane and whether the benefits of keeping the marriage surpass the benefits of getting rid of it.
Many of the problems with the marriage have nothing to do with the quality of the writers. As Peter Parker has a supportive wife, any attempt to shake up the status quo or move the series into a new direction will need to affect her too, which will cause events to be more extreme and add up fairly obviously. There are less private conflicts available than there are for a single Spider-Man. It will be a herculean effort to convince readers that Peter and Mary Jane may not be together at year’s end, especially without repeating the stories that have already been done (Peter and Mary Jane are separated, Mary Jane is believed dead, etc).
By the writer's imagination argument, they should be able to work with any limitation. So if Alonso decrees that the only supervillain Spider-Man can fight is the Vulture, the writers shouldn't complain. Solid writers could probably do good stuff for a while, regardless of the constraints (IE- if they were told that they can't use webbing, and/ or can't use any Lee/ Ditko villains, and/ or can't have use any of the Daily Bugle supporting cast) but that hardly serves as a justification for narrowing their options.
And some of the problems won't be solved by switching writers. If Writer A shakes up the status quo every now and then by jeopardizing Mary Jane, the next guy will be less able to do so as he can't really repeat anything Writer A has done, or the stuff that's already happened to the couple (Mary Jane leaves Peter to find herself, MJ gets pregnant.)
I might have one year in which Mary Jane disappears without a trace with no warning of any sorts, followed by two years of the couple being relatively happy and stable, followed by one year of Mary Jane getting progressively sicker for an initially unknown reason, followed by one year of the couple being relatively happy and stable, followed by one year of Peter sending Mary Jane into hiding, as he deals with a grave threat who wouldn't hesitate to use her against him. It's not a great long term strategy, as eventually this stuff would add up, in addition to all of the other stuff that's already happened to the couple.